Tel Aviv University

Professor Yael Hanein, Tel Aviv University Center for Nanoscience and Nanotechnology

The lab of Prof. Yael Hanein at Tel Aviv University specializes in micro and nano systems, in particular,
neuronal interfaces and lab on a chip technologies. The lab was established in 2003  as one of six core laboratories of Tel-Aviv University Center for Nanoscience and Nanotechnology. The lab is also affiliated with the Sagol School of Neuroscience and the Tel Aviv University School of Electrical Engineering.

As a part of the BMST project we investigate novel electrode-tissue technologies based on nanomaterials for DBS and EEG applications. In the frame of this effort we have previously developed unique technologies and abilities. In particular, coating and characterization processes allowing us to fabricate particularly small electrodes without diminishing its recording and stimulation performances, as well as fabrication of electrodes on flexible substrates.

Carbon Nanotube Neuronal Multi Electrode Array

In the last several years we have developed a novel class of micro electrodes for neuronal recording and stimulation. The electrodes are fabricated by synthesizing high density carbon nanotube (CNT) electrodes in a lithographically defined pattern on a silicon substrate. The highly porous 3D CNT interface supports strong coupling with the neuronal tissue as well as the formation of an electrochemically safe interface.

 

 

Main Features

  • High surface area - 3D electrodes
  • High specific capacitance: 10 mF/cm2
  • Rapid tissue-electrode coupling
  • Inert – redox-free cycles
  • No need for adhesion promoters
  • Suitable for multiple use
  • Biocompatible

 

All-Carbon Nanotube Flexible Electrodes

Recently, we have developed flexible electrode arrays based entirely on CNT technology. The enhanced electrochemical properties of the electrodes, their flexible and simple micro-fabrication preparation procedure as well as their bio-compatibility and durability suggest that such flexible CNT electrodes are a promising platform for both implanted high resolution neuronal coupling and for adhesive dermally applied EEG electrodes.

References

  • Semiconductor Nanorod–Carbon Nanotube Biomimetic Films for Wire-Free Photostimulation of Blind Retinas, Lilach Bareket, Nir Waiskopf, David Rand, Gur Lubin, Moshe David-Pur, Jacob Ben-Dov, Soumyendu Roy, Cyril Eleftheriou, Evelyne Sernagor, Ori Cheshnovsky, Uri Banin, Yael Hanein, Nano Letters,doi: 10.1021/nl5034304, 2014.
  • Carbon nanotube based micro electrode arrays for neuronal interfacing: Progress and prospects, Lilach Bareket and Yael Hanein, Frontiers in Neural Circuits, doi: 10.3389/fncir.2012.00122, 2013.
  • All-carbon-nanotube flexible neuronal electrodes, Moshe David-Pur, Lilach Bareket, Giora Beit-Ya’akov, Dorit Raz-Prug, Yael Hanein, Biomedical Microdevices, doi: 10.1007/s10544-013-9804-6, 2013.
  • Engineered neuronal circuits shaped and interfaced with carbon nanotube microelectrode array, Mark Shein, Alon Greenbaum, Tamir Gabay, Raya Sorkin, Moshe David-Pur, Eshel Ben-Jacob, Yael Hanein, Biomedical Microdevices, doi: 10.1007/s10544-008-9255-7, 2008.
  • One to one neuron-electrode interfacing, Alon Greenbaum, Sarit Anava, Amir Ayali, Mark Shein, Moshe David-Pur, Eshel Ben-Jacob and Yael Hanein, Journal of Neuroscience methods, doi: 10.1016/j.jneumeth.2009.06.012, 2009.

More Info:
http://nano.tau.ac.il/hanein

https://en-engineering.tau.ac.il/school-of-electrical-engeneering/news/tattoo

http://www.timesofisrael.com/tel-aviv-us-electronic-tattoo-said-to-read-your-face-and-emotions/

 

Contact Info:

Email: yaelha@tauex.tau.ac.il
Mail address: Prof. Yael Hanein, School of Electrical Engineering and Tel-Aviv University Center for Nanoscience and Nanotechnology, Tel-Aviv University, Ramat-Aviv, Tel-Aviv, 6997801, Israel.

Email: lilachb2@post.tau.ac.il
Mail address: Dr. Lilach Bareket, Tel-Aviv University Center for Nanoscience and Nanotechnology, Tel-Aviv University, Ramat-Aviv, Tel-Aviv, 6997801, Israel.