About Us

The Brain Stimulation-Monitoring-Treatment or BSMT consortium has been organized and financed by the MAGNET Program of the Chief Scientist Officer (CSO) of the Israeli Ministry of Economy. The consortium consists of 5 industrial companies (AlphaOmega LTD, Brainsway LTD, ElMindA LTD, Or-Nim LTD, Insightec LTD) and 11 research groups from 6 different academic institutions.

The purpose of the consortium is to establish generic technologies for the integration of neurostimulation technologies with monitoring technologies for the ultimate goal of treating brain diseases with a system based on the principles of closed-loop feedback and personalized treatment. These aims are closely linked to the goals of the discovery and utilization of neuro-markers of brain disorder to optimize treatment. This represents a topical, emerging area with huge potential for in the development of radically new ways of treating disease.

The neurostimulation technologies available to the partners in the consortium include deep transcranial magnetic stimulation (dTMS), focused ultrasound (FUS) and deep brain stimulation (DBS). The monitoring technologies include electroencephalograms (EEG), wherein the EEG signals are analyzed in order to deliver networks ( BNA), non-invasive monitoring of blood hemodynamics, magnetic resonance imaging (MRI), micro-electrode recordings (MER) and other intracranial recordings.

Neurostimulation technologies such as TMS and DBS are being increasingly used in the clinical treatment of neuropsychological disorders and conditions such as depression, due to their partial effectiveness at treating states of the condition that have normally been considered treatment-resistant based on conventional (usually, pharmaceutical) treatment. However, uptake of these technologies into the clinical mainstream is still relatively slow. Similarly, monitoring technologies such as EEG have proved very effective for diagnosis and examination of disease progression. However, their use to inform and optimize treatment in a real-time fashion has largely not been exploited. The goal of the consortium is therefore to improve the efficiency of treatment with neurostimulation by development of closed-loop feedback from monitoring technologies, thereby promoting the economic growth of both arms.